Which research does Breakthrough T1D fund?

Breakthrough T1D funds research into different fields of treatment, curing and prevention of Type 1 Diabetes. More information about Breakthrough T1D Grants and research areas can be found here.

Electronic Application System

For all Breakthrough T1D schemes the application, review and award process is centralised through our office in New York.

Information on how to apply via our online system can be accessed here.

Application Review Process

Decisions on funding are based on the quality, mission relevance, and priority of the proposed research. We encourage submission of innovative, high-risk/high-reward, field-changing research proposals to accelerate its mission. Information on our research strategy and current priorities can be found here. In addition to the process below, generally, applications undergo a pre-review process.

ADMINISTRATION CHECK

The first hurdle applications have to pass is an ‘administration’ check. Applications that are not completed properly or do not fit in with our overall strategy are eliminated first.

STAGE 1

At stage 1 our scientific team carries out the first review. They call on external reviewers and advisory committees (including lay members) to advise them on most applications. And all applications for larger amounts of funding, all clinical studies and all opportunities involving companies are reviewed in this way. To assess the scientific merit and validity of any proposal, criteria for review include:

  • Scientific validity and merit of proposed research
  • Technical feasibility of proposed research
  • Significance of the research:
    • Impact on accelerating discovery, development, or evaluation of type 1 diabetes therapeutics
    • Potential translation to human type 1 diabetes
    • Addressing a critical research gap
  • Innovation:
    • Potential for change in a paradigm
    • Potential for a seminal discovery
    • Novel approaches to solving a problem
  • Ability to complete the research in the funding period

STAGE 2

The applications that make it past stage 1 are then looked at by the senior management team of our Research department. This team decides on how each application fits in with our research strategy and our specific research goals. This team is particularly interested in projects that they think can be developed into real therapies fastest. Additional criteria for review include:

  • Relevance of the proposed research to our overall goals
  • Relevance of the proposed research to specific research priorities
  • Relevance of the proposed research in complementing our existing project portfolio

STAGE 3

If the application makes it to stage 3, the final decision on whether the project gets funded rests with the Breakthrough T1D president (for projects with smaller budgets) or, for all other projects, with the executive research committee of our board of directors (approximately half of this committee are lay people).

Contact us

Contact Breakthrough T1D the Netherlands for any questions you might have at info@breakthrought1d.nl